Functional capacity in Chagas disease

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Functional capacity and right ventricular function in patients with Chagas heart disease.

AIMS Right ventricular (RV) dysfunction is an important factor on effort tolerance in cardiopulmonary diseases. Nevertheless, the role of RV function in predicting exercise capacity in patients with Chagas disease has not been reported. This study aims to evaluate whether RV function assessed by tissue Doppler can predict functional capacity in patients with Chagas heart disease. METHODS AND ...

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[Maximal functional capacity, ejection fraction, and functional class in Chagas cardiomyopathy. Are these indices related?].

OBJECTIVE Left ventricular ejection fraction (LVEF) and maximal functional capacity (VO2max) have both been shown to be related to a poor long-term survival in Chagas' disease patients. The aim of this study was to estimate the potential association of VO2max, LVEF, and NYHA functional class in patients with Chagas' disease cardiomyopathy. METHODS One hundred four male patients, aged 40.3+/-9...

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Resveratrol Reverses Functional Chagas Heart Disease in Mice

Chronic chagasic cardiomyopathy (CCC) develops years after acute infection by Trypanosoma cruzi and does not improve after trypanocidal therapy, despite reduction of parasite burden. During disease, the heart undergoes oxidative stress, a potential causative factor for arrhythmias and contractile dysfunction. Here we tested whether antioxidants/ cardioprotective drugs could improve cardiac func...

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[Maximal functional capacity and diastolic function in patients with cardiomyopathy due to Chagas' disease without congestive heart failure].

PURPOSE To identify early cardiac dysfunctions in asymptomatic patients with Chagas' cardiomyopathy. METHODS We studied 38 male individuals: control group consisting of 20 sedentary normal individuals and Chagas' group, of 18 asymptomatic patients with Chagas' disease, with suggestive electrocardiographic alterations and normal fractional shortening (FS) on echocardiogram. Both groups were su...

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ژورنال

عنوان ژورنال: Revista da Sociedade Brasileira de Medicina Tropical

سال: 2018

ISSN: 1678-9849,0037-8682

DOI: 10.1590/0037-8682-0324-2018